Ok, I'm a little slow to discover this one. There's a great radio game show on NPR called Ask Me Another. The hook for me is that Jonathan Coulton is part of the show, and more Coulton is always a good thing.
The shows aren't long (10-12min) and well worth your time.
The most recent episode (Two Tickets to Parodies) featured Coulton playing covers of Weird Al Yankovic songs and the contestants had to finish the song lyrics with Weird Al's lyrics. Really funny!